Search results for blood-brain barrier

“POMC bound to sEVs crossed layers of endothelial cells (cells that line blood vessels) and a laboratory model of the blood–brain barrier more efficiently than free POMC. After crossing barriers in lab models, vesicle-bound POMC produced a measurable response in test cells.”

“Evidence indicates that white matter hyperintensities are predictive of the amount and degree of leakage of the blood-brain barrier leakage. Learn more in our overview article. View full publication.”

“Phosphatidylcholine is a very important component of cell membranes that make up neurons and also combines with the omega-3 fatty acid DHA to form lysophosphatidylcholine DHA which is transported across the blood-brain barrier.”

“While no of this data proves causation, there is a growing body of research showing that excess refined sugar does increase inflammation which crosses the blood-brain barrier and acceleration brain aging.”

“One of the major regulators of neurogenesis is the growth factor BDNF. Studies have shown 30 minutes of exercise can increase BDNF in humans. BDNF is able to cross the blood-brain barrier and promote the growth of new neurons.”

“Omega-3 fatty acids help maintain blood-brain barrier integrity and may reduce the risk of Alzheimer's disease in APOE4 carriers. Learn more in this open-access peer-reviewed article by Dr. Rhonda Patrick. View full publication.”

“00:37:16 - Some of the improvements seen in rodent research in terms of healthspan, but also memory and brain function, from a cyclical ketogenic diet. _See the episode with Dr. Eric Verdin for a discussion on this research.”

“One of the mechanisms linking cardiovascular disease, obesity, and dementia is vascular dysfunction, which contributes to blood-brain barrier failure. Learn more about vascular dysfunction in this clip featuring Dr. Axel Montagne.”

“There were no significant associations between CRP levels and memory, verbal fluency, category fluency, or overall cognition. One of the many ways inflammation harms the brain is through its effects on pericytes, tiny cells that surround the brain's blood vessels and help maintain the blood-brain barrier.”

“Even though BDNF is known to cross the blood-brain barrier, whether blood levels of BDNF are reflective of BDNF activity in the brain is unclear. Establishing blood biomarkers of dementia risk provides the ability for early intervention.”