What FoundMyFitness Has Covered
PremiumNeurons are central to movement, cognition, and brain maintenance, but their loss or dysfunction is implicated in several neurological disorders. Parkinson’s disease involves destruction of dopamine-producing neurons, particularly within motor circuitry, with symptoms emerging after substantial…
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Based on available source text from 8 of the first 10 results.
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How loss of dopamine-producing neurons affects brain circuitry and behavior | Giselle Petzinger
“Diagnosis of Parkinson's disease occurs at the onset of motor symptoms when half or more of the brain's dopamine-producing neurons are lost. Dopaminergic neurons are lost initially in the motor circuit of the brain, known as the basal ganglia, which is responsible for automatic movements, for example, balance.”
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Preventing brain aging with exercise — why to workout vigorously | Axel Montagne, Ph.D.
“Brain health depends on periods of high heart rate. Failing that, brain capillary health is compromised, and neurons are lost. In this clip, Dr. Axel Montagne highlights how 90 percent of our brain vasculature are tiny blood vessels - without exercise, they collapse, and neurons die.”
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How changes in cellular identity and stem cell differentiation affect epigenetic age
“Methyl patterns are crucial for a cell's maintenance of identity. As techniques are developed to differentiate and transdifferentiate cells from one cell type, such as a fibroblast, into another, such as a neuron, interesting patterns of effects on epigenetic age are revealed.”
Aliquot #55: Dietary strategies to improve symptoms of autoimmune disorders such as multiple sclerosis
“Multiple sclerosis (MS) is an autoimmune neurodegenerative disorder that destroys myelin, the insulating layer that surrounds neurons. The causes of MS are complex and may arise from both genetic and environmental factors, including nutritional deficiencies.”
Aliquot #21: Exercise to Fight Parkinson's Disease
“It typically manifests later in life and is caused by the destruction of neurons that produce dopamine. A growing body of evidence points to exercise's ability to reduce the risk of developing Parkinson's disease.”
BDNF
A growth factor involved in supporting and encouraging grwoth of new neurons and synapses.
Brain-derived neurotrophic factor (BDNF)
“Stem cells can be found in many tissues throughout the body, including the brain. Neural stem cells generate new neurons and glial cells, and several studies have tested their abilities in animal models of neurodegenerative diseases.”
Small vessel disease
“Parkinson's disease is characterized by motor neuron dysfunction, resulting in tremors, muscle rigidity, and movement difficulties. However, some people with the disease may also experience depression and cognitive impairment.”
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