Search results for stem cells

“"The epigenome is a set of mechanisms inside a cell that regulates which genes turn on and turn off. So when stem cells don't receive enough vitamin C, the epigenome can become damaged in a way that increases stem cell function but also increases the risk of leukemia."”

“Dr. Shinya Yamanaka discovered a group of proteins that can reprogram differentiated (mature) cells into pluripotent stem cells. These proteins, now called Yamanaka factors, are highly expressed in embryonic stem cells in mice and humans.”

“This new technology has broad implications for treatment of many age-related diseases like Parkinson's, ALS, type 1 diabetes and more. The reprogramming different cells into pluripotent stem cells that can form any cell type in the body along with gene editing (CRISPR) that can remove a faulty gene and replace with normal gene is world-changing!”

“The activation and increase in stem cells in the dental pulp causes the stem cells to form odontoblasts (specialized tooth cells) and also increases the production of dentine. This allows for cavities to be reversed.”

“Dental pulp stem cells are also found in adult teeth although to a much lesser degree. Dental pulp stem cells have been shown in animal studies to differentiate into other cells types including connective tissue and neurons in the spinal cord.”

“Mice genetically altered to have conditions similar to Alzheimer's disease fail to engage in nesting behavior. However, mice that received modified cells demonstrated improved nesting behavior and better spatial memory than those receiving unmodified stem cells.”

“These neural stem cells were formed from the skin cells of an 86 year old man!”

“The vitamin A activates the enzyme (called TET) that removes methyl groups from DNA and vitamin C is a cofactor for the enzyme. This not only has relevance for reprogramming adult cells into stem cells, it is also important for certain cancers such as acute promyelocytic leukemia, which abnormal methylation plays a role in malignancy.”

“From the article: > Lee and his colleagues tested 880 bioactive substances – including drugs and vitamins – approved by the U.S. Food and Drug Administration (FDA) to see if they stimulated the mouse stem cells to become heart muscle cells.”

“In experiments on mice, the stem cells were genetically engineered to produce and secrete toxins which kill brain tumors, without killing normal cells or themselves.”