Search results for genome

“DNA damage interferes with the sirtuins' role in gene regulation in a manner similar to aging A critical aspect of aging is genomic instability – a wide range of alterations that occur in our DNA and irreversibly change the information carried in our genome.”

“A recent study analyzed the genomes of multidrug-resistant Acinetobacter baumannii and the bacteriophages used against it. Bacteriophages (often referred to simply as "phages") are viruses that infect bacteria.”

“Large randomized controlled trial finds that 70% of women with early-stage invasive breast cancer do not need chemotherapy in addition to hormone therapy based on a genomic test for this type of breast cancer.”

“Using blood samples collected from the participants, the investigators conducted whole-genome sequencing to identify genetic differences between the two groups and to create a risk score for cardiovascular disease, the leading cause of death worldwide.”

“The bright light exposure activated the prefrontal cortex. Exposure to bright light in the morning is what sets the biological clocks (circadian rhythm) that regulate 15% of the human genome including genes that produce neurotransmitters.”

“Alterations in magnesium and oxidative status during chronic emotional stress - Young adults undergoing persistent or intermittent stress like anticipating military conflict) experienced substantial decreases in their overall and plasma magnesium concentrations over three months.”

“FTA: > HIV, the virus that causes AIDS, has the ability to integrate into the human genome, making it extremely difficult to cure the infection. A new study found that when HIV integrates into genes involved with cancer, these cells tend to reproduce to a greater extent than others HIV-infected cells.”

“The authors went on to posit that the similarities between obesity and aging are driven by shared molecular- and cellular-level mechanisms, including increased levels of reactive oxygen species, mitochondrial dysfunction, cellular senescence, increased apoptosis, impaired autophagy, and increased inflammation.”

“Latent viruses, the kind we don't even know we have, can have subtle effects like being associated with the development of cancer (in the case of herpes simplex almost everyone carries one form of the virus). That's why it's very interesting that we may actually have a future in which these viruses can be removed from our genome, thanks to CRISPR.”