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Circadian rhythms coordinate sleep–wake timing with metabolism, cognition, performance, and disease susceptibility. Disruption from shift work, jet lag, and modern lifestyles is associated with metabolic dysfunction, while the timing of food may matter because melatonin and…

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Melatonin

Jul 28, 2026

“In a vicious cycle, these disrupted rhythms also contribute to many Alzheimer’s-disease-associated pathways. Supplementing with melatonin may act as a “circadian shield”—a way to maintain normal rhythms in hope of preventing cognitive decline and a way to restore rhythms to slow disease progression.”

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