Dr. Rhonda Patrick examines hydrogen-rich water for inflammation, oxidative stress, lipids, and exercise recovery. ... exercise metabolism omega-3 inflammation rhonda oxidative stress cardiovascular supplements

[toc position='left'] Biological aging clocks are among the most important tools in modern longevity science. They attempt to answer a deceptively simple question: can we measure how fast a person is aging biologically, rather than just counting the number of years they have been alive? The answer is yes—but with important caveats. Epigenetic clocks use patterns of DNA methylation, a chemical tagging system on DNA, to estimate different aspects of aging. Some clocks estimate chronological age. Others predict disease risk, mortality risk, or the current pace of biological aging. This means biol... epigenetics aging telomeres genetics stem cells omega-3 dna damage biomarkers vitamin d senescence multivitamin

Dr. Rhonda Patrick discusses supplement timing, exercise timing, supplements in older adults, folic acid vs. folate, and hydrogen-rich water. ... rhonda folate sulforaphane supplements urolithin a cocoa exercise antioxidant Ubiquinol

[toc position='left'] Aging refers to the collective physiological, functional, and mental changes that accrue in a biological organism over time. The hallmarks of aging are observable biological patterns of dysfunction that occur with aging. Integral to the aging process is inflammaging, the chronic, low-grade inflammation that occurs with aging.[ref doi='10.1111/j.1749-6632.2000.tb06651.x'] The mechanisms that drive inflammaging and the pathological conditions that arise because of it are bidirectional and involve multiple physiological processes and pathways, many of which directly or indir... mitochondria aging omega-3 stem cells aerobic senescence

Dr. Mark Mattson discusses how stress is essential to human survival and how exercise and intermittent fasting induce stress to promote health. ... fasting exercise alzheimer's inflammation stress time-restricted eating

Dr. Patrick covers vitamin C's diverse aspects: bioavailability, immune function, viral protection, lung health, cancer impact, exercise effects, and more! ... vitamin c exercise cancer depression dna damage immune system oxidative stress autoimmunity

[toc position='left'] Background Vitamin C, also known as ascorbic acid, is an essential nutrient, widely recognized for its antioxidant properties. These properties arise from its potent redox potential due to its capacity to donate electrons to oxidized molecules. Even in small quantities vitamin C can protect critical molecules in the body such as proteins, lipids, carbohydrates, and nucleic acids (DNA and RNA) from damage by reactive oxygen species, which are generated during normal metabolism, by active immune cells, and through exposure to toxins and pollutants (e.g., certain chemotherap... cancer nutrition exercise interesting

[toc position='left'] Creatine is a naturally occurring compound that is critical in storing and releasing cellular energy. It also participates in many biological processes driving pregnancy outcomes, maintaining bone mineral density and muscle mass in older adults, improving neurological function, and aiding the immune system to fight cancer. Creatine is best known for its widespread use as a dietary supplement to enhance physical performance. Creatine uptake, synthesis, storage, and supplementation Creatine uptake Creatine can be supplied exogenously (from dietary or supplemental sources) ... metabolism neurodegeneration nutrition brain aging depression pregnancy

Dr. Rhonda Patrick makes her second appearance on the Joe Rogan Experience. ... rhonda vitamin d nutrition brain diet obesity epigenetics aging sleep dna damage vitamin e sauna