Episodes
Cold-water immersion increases norepinephrine circulation, triggering adaptive effects on metabolism, the brain, and gene expression.
Dr. Rhonda Patrick summarizes research associating sauna use with lower mortality: 2–3 weekly sessions with 24% lower risk and 4–7 with 40%.
Melatonin production rises 2–3 hours before typical bedtime, which may signal the pancreas to begin suppressing insulin production.
Dr. Peter Attia discusses dietary strategies to promote longevity and optimal performance.
Dr. Valter Longo on Resetting Autoimmunity and Rejuvenating Systems with Prolonged Fasting & the FMD
Dr. Valter Longo discusses fasting as a means to treat or prevent age-related diseases such as cancer, Alzheimer’s disease, and others.
Sauna use boosts lifespan and overall health supported by compelling data from observational, interventional, and mechanistic studies.
There may be something special about sources of omega-3 that are richer in the phosphatidylcholine form of DHA.
Dr. Guido Kroemer discusses immunology, cancer biology, calorie-restriction mimetics, aging, and autophagy.
Dr. Dominic D'Agostino discusses the health benefits associated with a modified Atkins diet, ketosis, and supplemental ketones.
Tim Ferriss discusses ketosis, the gut microbiome, and monitoring biomarkers to promote performance.
Dr. Mark Mattson discusses how stress is essential to human survival and how exercise and intermittent fasting induce stress to promote health.
Wim Hof discusses his unique breathing technique and how it helps him withstand cold stress.
Dr. Andy Galpin & Dr. Rhonda Patrick discuss nutrition, supplement, and recovery strategies for improving exercise performance.
Dr. Patrick explains how magnesium deficiency may impair mitochondrial oxidative capacity and how adequate intake could support exercise performance.
A special two-hour Q&A with Dr. Jed Fahey, an expert on sulforaphane, chemoprotection, and phytochemicals.
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