Search results for genetics

“From the article: > "The BDNF gene has previously been linked to obesity, and scientists have been working for several years to understand how changes in this particular gene may predispose people to obesity," said Jack A. Yanovski, M.D., Ph.D. [...] > The BDNF protein plays several roles in the brain and nervous system and, at high levels, the protein can stimulate the feeling of fullness.”

“Not only is salmon roe a good source of DHA, it also provides protein, vitamins, minerals, and astaxanthin – an antioxidant compound that gives salmon its reddish or pinkish tint. In human studies, astaxanthin reduces biomarkers of oxidative stress.”

“A related mouse experiment used chemical and genetic activation of hypothalamic neurons to induce a torpor-like state, a state of reduced activity similar to hibernation. Over four days, body temperature fell by nearly 10°F, or about 7°C; metabolic rate fell by about 56%; and food intake fell by about 81%, with recovery after removal of the stimulus.”

“Their own T cells were used for the strategic addition of a specialized receptor specific to a marker expressed by the cancer cells (CD19).”

“Clinicians have regularly observed that their patients' insulin sensitivity worsens in the evening hours. Genetic studies have revealed that carriers of a variant of the melatonin receptor gene (MTNR1B) are more likely to have obesity or diabetes.”

“- Axel Montagne, Ph.D. A variant of the APOE gene called APOE4 is the primary genetic risk factor for late-onset Alzheimer's disease. Carrying one copy of APOE4 increases a person's Alzheimer's disease risk two- to threefold; carrying two copies increases a person's risk as much as 15-fold.”

“However, this newly identified sub-type of APOE4 markedly alters that risk and adds complexity to discussions about the role of genetics in Alzheimer's disease. These findings suggest that some variants of the APOE gene may be protective against Alzheimer's disease.”