Search results for small vessel disease

“The analysis of cfRNA and exosomes (small vesicles containing cellular components released by living cells) could provide a minimally-invasive alternative for identifying hypertensive disorders of pregnancy and gestational diabetes mellitus., Additionally…”

“The health of the blood vessels that comprise the blood-brain barrier may also be a critical and early pathological feature of Alzheimer's disease and other dementias. Environment and lifestyle also contribute to Alzheimer’s disease risk, and sleep is one of the most well-recognized modifiable lifestyle factors.”

“Lifestyle habits or drugs that increase beta-hydroxybutyrate may extend healthspan and reduce disease risk by slowing the rate of senescence. The researchers conducted an experiment that involved culturing human vascular endothelial (i.e., blood vessel cells) from the umbilical cord and aorta, followed by an experiment with mice.”

“High blood pressure increases a person's risk for heart disease and stroke and contributes to small vessel disease, a major risk factor for cardiovascular disease, dementia, and stroke. However, lifestyle factors, such as sauna use, help maintain healthy blood pressure.”

“Osteocalcin is produced in the bones and promotes calcium accretion in the bones and teeth Matrix Gla protein is produced in the smooth muscle cells of blood vessels and plays critical roles in inhibiting vascular calcification, a process associated with the development of cardiovascular disease and renal dysfunction.”

“The fatty acids may also protect the brain against white matter hyperintensities – areas in the brain that often indicate cerebral small blood vessel disease, a risk factor for dementia.”

“Start with well-tolerated light and moderate activity, and gradually sprinkle in very short bursts of higher effort. Of course, medical clearance and supervision (as in cardiac rehab programs) are crucial for people with known heart disease or high risk.”

“High blood pressure increases a person's risk for heart disease and stroke and contributes to small vessel disease, a major risk factor for cardiovascular disease, dementia, and stroke.”

“They also underwent brain scans that measured their brain volumes and identified the presence of white matter lesions – areas in the brain that often indicate cerebral small blood vessel disease, a risk factor for dementia.”

“The resulting inflammation damages healthy cells via oxidative damage and directs their behavior, a type of intercell communication called a paracrine effect. Summaries Below is a selection of summaries from current research investigating the role of senescence in health and disease.”