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“If future, longer-term studies show that these benefits last and can be reproduced in other settings, structured exercise that combines movement with cognitive tasks could become a practical non-drug option for children with ADHD in schools, clinics, and community programs.”

“The drug mimics GLP-1, a hormone that helps the pancreas release insulin and the brain regulate appetite. But certain cells in the heart, blood vessels, and other tissues also carry GLP-1 receptors, allowing them to respond to the same signal.”

“People who have had colon polyps removed remain at risk of new growths, and preventive drugs either cause side effects or lack long-term evidence. Researchers in China revisited a randomized controlled trial of the compound berberine to test whether a two-year course could provide durable protection.”

“After a baseline observation period of nine days, monkeys were randomly selected to receive a daily injection of either a sterile saline solution (placebo) or a pharmacological analog of the liver hormone FGF21 for a total of 16 days. The FGF21-mimicking drug was found to produce a 50 percent reduction in alcohol consumption, without influencing the monkeys’ intakes of food or water.”

“Psyllium was taken in daily amounts ranging from 7 to 15 grams. The combination produced modest but meaningful improvements in cholesterol levels: Across all trials, adding psyllium led to an additional drop in LDL cholesterol compared to taking a statin alone.”

“The analysis used data from the Coronary Artery Risk Development in Young Adults (CARDIA) study, which enrolled 5,115 adults aged 18 to 30 in the mid-1980s and followed them for more than 30 years.”

“Finally, they conducted a randomized, double-blind, placebo-controlled trial in healthy human participants (average age, 28 years). The participants consumed either 50 milligrams or 200 milligrams of avocatin B per day or a placebo for 60 days in order to determine the safety of the drug.”

“Then they examined whether the mice preferred only sucrose-containing solutions or a high-fat diet after being food deprived. Finally, they administered a dopamine-inhibiting drug to the mice to determine if dopamine signaling influenced the mice's eating behaviors.”

“Metabolic dysfunction escalates with age and increases the risk of frailty and chronic disease. Many investigational antiaging drugs target enzymes involved in energy metabolism, such as mammalian target of rapamycin (mTOR) and insulin-like growth factor (IGF)-1.”

“Lifestyle habits or drugs that increase beta-hydroxybutyrate may extend healthspan and reduce disease risk by slowing the rate of senescence. The researchers conducted an experiment that involved culturing human vascular endothelial (i.e., blood vessel cells) from the umbilical cord and aorta, followed by an experiment with mice.”