FOXO
“FOXO1 binds to insulin-response elements to increase hepatic gluconeogenesis, a robust contributor to hyperglycemia in the setting of diabetes. FOXO1 represses PPARγ1 and PPARγ2 promoter activity, driving insulin resistance.”
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Found 824 matches across the FoundMyFitness library.
“FOXO1 binds to insulin-response elements to increase hepatic gluconeogenesis, a robust contributor to hyperglycemia in the setting of diabetes. FOXO1 represses PPARγ1 and PPARγ2 promoter activity, driving insulin resistance.”
“The patients were between the ages of 19 and 77 years, and the majority had at least one underlying health problem, such as diabetes, high blood pressure, abnormal cholesterol levels, or other conditions.”
“Insulin resistance increases a person's risk of developing type 2 diabetes and atherosclerosis. Findings from a new study suggest that lean beef as part of a healthy dietary pattern may reduce this risk in people with insulin resistance.”
“Visceral fat interferes with lipid metabolism in the liver, promoting insulin resistance, type 2 diabetes, and non-alcoholic fatty liver disease. A diet that includes avocados, which are rich in mono-unsaturated fats and dietary fiber, is associated with lower abdominal obesity.”
“It is involved in many physiological processes, including energy production, nucleic acid and protein synthesis, ion transport, and cell signaling. Magnesium deficiency is linked with increased risk of cardiovascular disease, osteoporosis, hypertension, and type 2 diabetes.”
“Examples include type 1 diabetes, Hashimoto’s thyroiditis, lupus, and multiple sclerosis. The authors of the study recruited male and female health care workers who had been infected with SARS-CoV-2 and were either symptomatic or asymptomatic for COVID-19.”
“Exposure to air pollution promotes oxidative stress and increases the risk of developing many chronic diseases, such as cardiovascular disease, cancer, hypertension, and diabetes, markedly shortening people's lives.”
“Mitochondrial dysfunction, the disruption of normal mitochondrial function that occurs over time, is a driver of many chronic diseases, such as cancer, type 2 diabetes, and cardiovascular disease, and is a hallmark of aging.”
“Metabolic syndrome is a constellation of conditions characterized by abdominal (central) obesity, elevated blood pressure, elevated fasting plasma glucose, high serum triglycerides, and low high-density lipoproteins. Having metabolic syndrome increases a person's risk of cardiovascular disease and type 2 diabetes.”
“Periodontitis (a gum disease that can destroy the tissues that support the teeth) affects a large share of older adults and has been tied to conditions such as heart disease and diabetes.”
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