Whole-body hyperthermia as a treatment for depression: sauna, hot yoga and exercise | Charles Raison

Parent Episode: Dr. Charles Raison on Depression, the Immune-Brain Interface & Whole-Body Hyperthermia

Scientists exposed patients to high heat using an infra-red device or hot yoga and found both modalities to have anti-depressant effects. Heat stress causes the release of beta-endorphins as well as dynorphin, an endogenous opioid. Exercise produces similar results by releasing anti-inflammatory cytokines that may contribute to an anti-depressant outcome. In this clip, Dr. Charles Raison describes how whole-body hyperthermia has the potential for real-world clinical efficacy as a tool in the fight against major depression.

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