Episodes

How telomere length varies at birth and may impact longevity and healthspan | Elissa Epel

Posted on June 25th 2019 (almost 5 years)

Dr. Elissa Epel describes the effects of longer sperm telomere length on subsequent generations.

Genetics and microbiome affect individualized responses to a variety of foods | Elissa Epel

Posted on June 25th 2019 (almost 5 years)

Dr. Rhonda Patrick and Dr. Elissa Epel describe the factors that influence how we respond to diet.

Compressing the morbidity window - maximum longevity vs. healthspan | Elissa Epel

Posted on June 25th 2019 (almost 5 years)

Dr. Elissa Epel describes how even small lifestyle changes can have an effect on telomere length and healthy aging to compress morbidity.

Obesity affects genes in sperm DNA involved in metabolism and brain | Elissa Epel

Posted on June 25th 2019 (almost 5 years)

Dr. Rhonda Patrick and Dr. Elissa Epel discuss how obesity affects genes in sperm DNA involved in metabolic health and cognitive function.

Supplements that lengthen telomeres | Elissa Epel

Posted on June 25th 2019 (almost 5 years)

Dr. Elissa Epel discusses the pros and cons associated with taking dietary supplements to lengthen telomeres.

Telomerase repairs telomeres and prevents senescence, but is hijacked by 80 to 90% of cancers

Posted on June 25th 2019 (almost 5 years)

Dr. Elissa Epel discusses how cancer cells exploit the regenerative capacity of telomerase to perpetually divide, essentially becoming immortal.

Sugar-sweetened beverages associated with older biological age | Elissa Epel

Posted on June 25th 2019 (almost 5 years)

Dr. Elissa Epel discusses the harmful effects of what she calls a "toxic lifestyle," one that includes the consumption of sugar-sweetened beverages.

Aerobic exercise lengthens telomeres and buffers against losses caused by stress | Elissa Epel

Posted on June 25th 2019 (almost 5 years)

Dr. Elissa Epel describes some of the studies that demonstrate the links between healthy lifestyle behaviors like exercise and discusses potential mechanisms.

Small positive lifestyle changes made in midlife predict longevity | Elissa Epel

Posted on June 25th 2019 (almost 5 years)

Dr. Elissa Epel describes the "low hanging fruit" – small, healthy lifestyle behaviors – that can have positive effects on telomere length and lifespan.

What makes women live longer? | Elissa Epel

Posted on June 25th 2019 (almost 5 years)

Dr. Elissa Epel identifies some of the key differences in male and female biology and how they influence telomere length and aging.

Telomeres explained: role in genomic stability, stem cells, replicative senescence | Elissa Epel

Posted on June 25th 2019 (almost 5 years)

Dr. Elissa Epel gives a brief overview of telomeres and the enzyme telomerase and explains how they impact health and lifespan.

Telomere paradox: cancer risk vs. delayed senescence | Elissa Epel

Posted on June 25th 2019 (almost 5 years)

Dr. Elissa Epel discusses the importance of having an optimal ratio of telomerase to reduce the risk of chronic diseases and cancer.

Shorter telomeres can be transmitted epigenetically to offspring | Elissa Epel

Posted on June 25th 2019 (almost 5 years)

Dr. Elissa Epel explains how aging syndromes can be passed to offspring via epigenetic mechanisms.

Telomeres: controlling aging or just a biomarker? | Elissa Epel

Posted on June 25th 2019 (almost 5 years)

Dr. Elissa Epel describes how Mendelian randomization techniques provide insights into the dual nature of telomeres, as both a cause and a sign of aging.

How poor diet, environmental stress and chemical exposure affect telomeres | Elissa Epel

Posted on June 25th 2019 (almost 5 years)

Dr. Elissa Epel describes the exposome – the totality of non-genetic exposures a person experiences during a lifetime – and explains how it affects telomeres.

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