Search results for small vessel disease

Small vessel disease is a generic term that describes dysfunction of blood vessels that occurs with aging and contributes to cognitive decline, cardiovascular disease, frailty, and stroke.

“This relationship remained even after taking gender and age into account. Increased burden of white matter hyperintensities and lacunar infarcts, symptoms of cerebral small vessel disease, was associated with greater depression risk among 3,800 participants without dementia.”

“Cerebral small vessel disease is associated with amyloid-beta deposition in the brain, especially among APOE4 carriers. Small vessel disease is a collection of conditions characterized by damage to arterioles and capillaries, resulting in reduced or interrupted blood flow to the affected organ.”

“Alzheimer's disease, cerebral small vessel disease, and vascular dementia are the three most prevalent forms of dementia and can present simultaneously, exacerbating the associated cognitive losses.”

“The study involved 43 patients (average age 58 years) who had been diagnosed with cerebral small vessel disease, as evidenced by having experienced a stroke or demonstrating mild cognitive impairment.”

“Defined as having a systolic pressure of 130 or higher or a diastolic pressure of 80 or higher, high blood pressure drives small vessel disease, a major risk factor for a host of health problems, including cardiovascular disease, dementia, kidney problems, and stroke.”

“Celiac disease primarily affects the small intestine and is characterized by autoimmune destruction of intestinal microvilli triggered by gluten, a protein found in wheat and other grains.”

“A new study shows that having low bone density may increase a person's risk for cerebral small vessel disease – a driver of dementia. People with the lowest bone density in their upper femur were twice as likely to develop dementia over a ten-year period than those with the highest bone density.”

“Small vessel disease in the brain contributes to approximately 50 percent of dementia cases worldwide. Read full publication. Learn more about small vessel disease in our overview article.”

“To investigate creatine's effects on blood vessel health—specifically by measuring the ability of arteries and small blood vessels to increase in size to accommodate blood flow (known as endothelial function)—one study recruited 12 healthy men and women with an average age of 59 and supplemented them with creatine or a placebo for 28 days each.”