Search results for insulin resistance

“Sulforaphane improves blood glucose control in type 2 diabetes Type 2 diabetes is a progressive metabolic disorder characterized by high blood glucose levels and insulin resistance. A 2017 study demonstrated that sulforaphane reduces glucose production in the liver and improves blood glucose control.”

“These changes correlated with markers of inflammation and insulin resistance. Approximately 20 percent of teens living in the United States are obese. Obesity negatively affects multiple organ systems, including the nervous system.”

“00:08:06 - How the suppression of the IGF-1 pathway, typically a hallmark of prolonged fasting and caloric restriction studies and potentially needed for some of the benefits, may fail to be achieved in human caloric restricters that eat too much protein. 00:09:34 - How certain macronutrients influence the insulin/IGF-1/growth hormone axis interact to modulate aging in many cell types.”

“Cardiometabolic syndrome is a constellation of disorders that includes insulin resistance, impaired glucose tolerance, abnormal blood lipids, high blood pressure, and obesity. People who have cardiometabolic syndrome are more likely to die from heart disease or experience a heart attack or stroke than those without the syndrome.”

“Resistance training exercise is a highly effective strategy for maintaining or building muscle mass. A new study suggests that metformin, a drug commonly used to treat type 2 diabetes, blunts the effects of resistance training.”

“Participants completed 12 weeks of combined aerobic and resistance training in the morning (8 a.m. to 10 a.m.) or afternoon (3 p.m. to 6 p.m.). The researchers measured insulin tolerance, body composition, and exercise performance before and after the intervention.”

“Insulin resistance impairs this process, resulting in higher blood sugar and increased fat release into the bloodstream. Controls showed lower de novo lipogenesis (the liver's production of new fat from non-fat sources) at night, while MASLD participants kept this pathway elevated.”

“These physiological changes lead to higher baseline blood pressure levels and a greater risk of hypertension. Moreover, metabolic factors associated with obesity—such as insulin resistance, inflammation, and altered kidney function—further exacerbate sodium-related blood pressure increases.”

“Only the BFRT group improved mitochondrial respiration in fat tissue and reduced visceral fat, the fat stored deep in the abdomen around internal organs and strongly linked to insulin resistance and cardiovascular disease risk.”

“Aging leads to progressive muscle loss (sarcopenia), decreased strength, and functional decline, significantly affecting quality of life. Creatine supplementation, particularly combined with resistance training, has emerged as a valuable nutritional strategy to mitigate these negative consequences of aging.”