Search results for mitochondria

“Mitochondria Microplastic particles are small enough to penetrate cell membranes and accumulate inside cells, directly impacting mitochondria. Once there, these tiny plastics can cause noticeable structural changes, such as swelling and a loss of integrity in the mitochondria.”

Dr. Rhonda Patrick explains how vigorous exercise challenges mitochondria, glucose disposal, and cardiovascular fitness.

“> The researchers also discovered that these mice had increased concentrations of DHA in their brain mitochondria, energy-producing structures in cells that can be injured by free radicals when blood flow is restored to the brain after a stroke.”

“Dr. Rhonda Patrick reviews L-carnitine, CoQ10, alpha-lipoic acid, and PQQ, explaining how their biochemical roles connect to interest in supplementation. L-carnitine helps transport fatty acids into mitochondria.”

“During aerobic exercise, the body increases the delivery of fats to the muscle mitochondria and increases mitochondrial capacity to metabolize fats, a process called beta-oxidation. The inner membrane of mitochondria possesses a series of enzymes called the electron transport chain.”

“In a mouse model of Alzheimer's disease, in which mitochondrial dysfunction is commonly observed, mice that were injected with 100 mg/kg/bw of nicotinamide mononucleotide every other day for 28 days had improved brain mitochondria respiratory capacity.”

Dr. Rhonda Patrick explains how progressive aerobic training and intervals can improve cardiac stiffness, VO2 max, and mitochondria.

“Mitochondrial biogenesis, the process by which new mitochondria are produced in cells, is regulated by the transcription factor PGC-1α. SIRT1 promotes the synthesis of PGC1-α to induce mitochondrial biogenesis in several cell types.”

“Having healthy mitochondria is critical to endurance exercise, which utilizes an enormous amount of energy. When mice are restricted to a 9-hour window of feeding, their mitochondrial function in multiple tissues increases, and mitochondrial biogenesis – the production of new mitochondria – is enhanced.”

“The analysis revealed that photobiomodulation may favor the activity of slow-twitch motor units, improving muscle endurance and time-to-exhaustion performances. The researchers posited that highly trained athletes, who often have more muscle mitochondria, may respond better to photobiomodulation.”