What FoundMyFitness Has Covered
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Ketones shine in extreme exercise environments | Dominic D'Agostino
“But exogenous ketones may act to preserve performance and resilience in extreme environments, such as hypoxia. For example, there could be a rationale for using ketones to augment performance for people who are mountain climbing, running, or cycling.”
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Obesity, metabolic syndrome and depression, is inflammation the underlying link? | Charles Raison
“A linear relationship exists between obesity, inflammation, and response to medication. In this clip, Dr. Charles Raison discusses how a pro-inflammatory environment, such as that which occurs with obesity, can contribute to the risk of depression.”
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Blue light exposure and the importance of darkness at night as it related to depression
“Moreover, research shows that bright light therapy is helpful in the treatment of non-seasonal depression. In this clip, Dr. Charles Raison discusses how exposure to light during the day and maintaining a dark environment at night is important in depression management.”
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Early exposure to bacteria protects against autoimmune diseases in children
“Studies indicate that exposure to diverse microorganisms from soil or pet dander before the first year of life may decrease allergies and asthma in children. In this clip, Dr. Rhonda Patrick explains how allergens in the environment may shape the immune system during early life.”
Aliquot #5: Light exposure: Striking a balance for sleep and mental health
“Regulating the amount of light in our environment is crucial for a good night's sleep and a good mood the next day. Habits such as using blue light-emitting electronics close to bedtime can reduce melatonin production by as much as 20 percent, impairing sleep.”
Day–night patterns of light exposure
“Melatonin onset moved 1.4 hours earlier among nine campers, while five people who remained in the modern lighting environment shifted later over the weekend. The striking sleep duration result came from a separate winter arm with only five participants.”
Sauna
“Repeated heat exposure might briefly increase immune surveillance while promoting a less inflammatory baseline environment over time. That model is biologically plausible but has not been directly demonstrated. The respiratory evidence remains preliminary.”
People who were conceived in a cold vs warm environment had enhanced brown adipose tissue activity leading to better adaptation to overnutrition.
“People who were conceived in a cold vs warm environment had enhanced brown adipose tissue activity leading to better adaptation to overnutrition and cold stress. This phenotype appears to be paternally transmitted via epigenetic changes in sperm cells.”
Rapamycin
“mTORC2 also activates Akt, a protein that further promotes cell survival and growth pathways. While mTORC1 directly drives protein synthesis, mTORC2 ensures that the cellular machinery and environment are optimized for this process.”
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