Episode
Joe Rogan Experience #901 - Dr. Rhonda Patrick
“01:16:42 - Inflammation causes tryptophan – the precursor to serotonin – to be reallocated to kynurenine, which then turns into the neurotoxin quinolinic acid, leading to depression. Study. 01:18:00 - The many ways exercise and lifestyle can combat depression.”
Supplemental probiotics for 12 weeks improved cognition in Alzheimer's patients & also lowered inflammatory markers.
“Other studies have shown that gut bacteria are able to modulate the levels of GABA, norepinephrine, serotonin, dopamine, and acetylcholine through the gut-brain axis. I spoke with the gut experts, Drs.”
Taking questions on reddit for my new paper! Omega-3 & Vitamin D control brain serotonin, affecting behavior & psychiatric disorders.
“Here's the ScienceDaily link if you want the short and sweet.... and... Here's the actual journal link.”
Low maternal vitamin D levels in early to mid-pregnancy were associated with an increased risk for offspring ADHD.
“I published an article a few years ago first identifying how vitamin D regulates the conversion of the essential amino acid tryptophan into serotonin, and how this may influence the development of neurodevelopmental disorders such as autism spectrum disorder, ADHD, bipolar disorder, and schizophrenia, which all share as a unifying attribute low brain serotonin.”
Older adults who used psychedelics exhibited better cognitive function and fewer depressive symptoms than non-users.
“Psychedelic drugs primarily act on serotonin receptors, particularly the 5-HT2A receptor, altering perception, mood, and cognition. These changes in brain activity and connectivity may promote neuroplasticity, potentially benefiting overall cognitive function and mental health.”
[TIMELINE] Joe Rogan Experience #502 with Dr. Rhonda Patrick
“00:12:00 - Talks about how amygdala activation from either extreme excitement or fear increases episodic memory. 00:12:15 - Talks about her new paper and how serotonin plays a role in brain function/dysfunction, behavior, and episodic memory.”
Ketogenic diet may alleviate ADHD symptoms by altering gut microbiota and boosting neurotransmitter expression.
“In addition, both groups demonstrated elevated levels of various neurotransmitters, including serotonin, norepinephrine and others, in brain tissue, along with changes in the expression of key proteins related to neural signaling.”
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