Search results for drug

“The divergence suggests that the composition of rapid weight loss may depend on whether muscle can preserve the flexibility to switch toward alternative fuels when energy intake falls. In Aliquot #128, I examine how GLP-1 drugs promote weight loss, the trade-offs they may carry, and strategies that may help support long-term health.”

“While these drugs can be effective, they often have unwanted side effects. An altered eating pattern that involves fasting in the evening can also reduce Hemoglobin A1C – a measure of blood sugar over the past three months.”

“FTA: > Intermittent dosing with rapamycin breaks the inflammatory loop associated with senescence, scientists report. Once disrupted, it takes time for the loop to reestablish itself -- providing proof-of-principal that intermittent dosing could provide a way to reap the benefits of rapamycin while bypassing its safety issues. The FDA-approved drug increases healthspan and lifespan in mice.”

“In the early 1980s, intravenous drug users inadvertently injected a contaminated drug and developed parkinsonian symptoms overnight. An investigation uncovered previously unknown details about the disease that allowed researchers to develop animal models.”

“From the article: > A study has found that cancer patients suffering depression have decreased amounts of brain-derived neurotophic factor (BDNF) in their blood. Low levels make people less responsive to cancer drugs and less tolerant of their side-effects.”

“Clearing away senescent cells in the brain using senolytic drugs prevented brain degeneration in mice genetically prone to it. The diseased animals were able to form memories, eliminated signs of inflammation, and did not develop tangles in the brain.”

“Sulforaphane exerts its therapeutic effects through various mechanisms, such as inhibition of phase 1 drug-metabolizing enzymes, induction of phase 2 protective enzymes, and inhibition of cell proliferation. When used in conjunction with various anticancer treatments, sulforaphane appears to work in a synergistic fashion to potentiate the drugs' effects.”

“However, the study did not measure ESOD activity to assess copper status, which may be more clinically relevant than serum copper levels. Zinc supplementation and drug interactions Zinc supplementation can reduce the absorption of antibiotics such as cephalexin and tetracycline.”

“Long term toxicology studies in humans (longer than one year) have not been performed. Studies have also shown that resveratrol supplementation may interfere with the way in which the body metabolizes other drugs.”

“A recent editorial reports that many dietary supplements may be contaminated with heavy metals or microbes or may contain synthetic drugs or ingredients not listed on their labeling.”