Search results for resveratrol

“In healthy mammals, studies have yet to confirm that resveratrol supplementation extends lifespan. However, studies have shown that resveratrol supplementation can increase the lifespan of metabolically compromised animals.”

“In this episode, Rhonda gives a summary of the science of resveratrol including its effects in animals and humans, the mechanisms behind how it works, and the bottom line on resveratrol supplementation and safety. A few key moments... For a more in-depth timeline, as well as references for this episode, click the timeline tab. Learn more about resveratrol on our overview page”

“In particular, at high doses, resveratrol improved the monkeys' aortic stiffness by as much as 40 percent. In this clip, Dr. David Sinclair describes research demonstrating the beneficial effects of resveratrol on the cardiovascular system of monkeys.”

“Furthermore, it is relatively unstable and demonstrates poor bioavailability in humans. In this clip, Dr. David Sinclair identifies some of the practical considerations of resveratrol supplementation and discusses his personal use of the compound.”

“Furthermore, it is relatively unstable and demonstrates poor bioavailability in humans. In this clip, Dr. David Sinclair identifies some of the practical considerations of resveratrol supplementation and discusses his personal use of the compound.”

“In fact, some studies have shown that resveratrol has negative effects on endurance. In this clip, Dr. David Sinclair identifies some of the practical considerations of resveratrol supplementation and discusses his personal use of the compound.”

“In a simple analogy, NAD+ is the fuel in a car that the sirtuins are driving. To carry that analogy a bit further, resveratrol, a plant-based molecule found in red grapes and peanuts, acts as an accelerator to enhance the activity of the fuel – NAD+.”

“Resveratrol, a plant-based compound found in red grapes and peanuts, exerts beneficial effects on the human brain. Clinical trials have demonstrated that resveratrol reduces levels of amyloid-beta in cerebrospinal fluid and improves cognitive function in people with Alzheimer's disease.”

“These boosters enhance cerebral blood flow, mimicking exercise and promoting regrowth of the aging cerebral vascular system. In this clip, Dr. David Sinclair and Dr. Rhonda Patrick discuss the brain health benefits associated with resveratrol and NAD+ boosters.”

“When ingested by humans, resveratrol binds to sirtuins, altering their affinity for NAD+ and their protein substrates, thereby increasing sirtuins' activity. As such, resveratrol presents a promising therapeutic strategy to ameliorate age-related diseases and extend healthspan.”