Search results for aging

“00:16:45 - The emerging link between certain environmental heavy metal and chemical exposures diseases of aging and corresponding telomere attrition. BPA study; Heavy metal study. 00:17:35 - The emerging science of air pollution, where some evidence suggests that small particle exposure may increase telomere attrition.”

“Dr. Levine describes the cardiac-compliance change as roughly equivalent to reversing two decades of sedentary heart aging. That is a physiological comparison, not proof that exercise makes the whole body 20 years younger.”

“To carry that analogy a bit further, resveratrol, a plant-based molecule found in red grapes and peanuts, acts as an accelerator to enhance the activity of the fuel – NAD+. In this clip, Dr. David Sinclair describes the links between NAD+, sirtuins, and resveratrol in the aging process.”

“Different clocks capture different biology, and observational studies have associated higher omega-3 intake with favorable results on selected aging measures. The strongest randomized evidence comes from a post hoc DO-HEALTH analysis of 777 adults age 70 and older.”

Dr. Rhonda Patrick and Dr. Steve Horvath discuss COSMOS multivitamin findings for cognition and epigenetic aging in older adults.

“Without adequate muscle reserve built when young and preserved when old, we more quickly reach a "disability threshold." In this clip, Dr. Stuart Phillips discusses how building muscle reserves under adequate nutrition delays the disability threshold and contributes to more successful aging.”

“Another is the GrimAge clock (named creatively for the Grim Reaper), which predicts lifespan and healthspan in units of years and tests whether potential lifestyle interventions may slow or reverse biological aging.”

“In this clip, Drs. Levine and Patrick discuss the epigenetic changes that occur with age, including methylation of CpG sites. Using methods discovered in recent research, the program of cellular aging may be reversible without disrupting cell function.”

“Epigenetic clocks may be a potent way of gauging the successfulness of anti-aging interventions that is resistant to accidental artifact in the lab. In vivo, the epigenetic changes that occur over time as a person ages, Dr. Horvath says, are more stable than gene expression, proteomics, and metabolomics measurements.”

“Large cohorts associate more leisure-time activity with lower mortality. Resistance training supports lean mass and function in older adults. Dr. Patrick also cites a skin-aging study and describes a lower likelihood of collagen breakdown among physically active people.”