Search results for blood-brain barrier

“After the mice experienced a stroke, the authors measured the animals' Nrf2 and HO-1 gene expression and assessed behavioral changes, blood-brain barrier integrity, and neurological deficits.”

“The mice with kidney disease had twice as many microbleeds in their brains as healthy mice and showed signs of increased blood-brain barrier permeability. Fifty percent of the people who had kidney disease had microbleeds, whereas just 10 percent of those who were healthy had microbleeds.”

“Although this was a small study, it supports a growing body of evidence suggesting exercise is a potent strategy for staving off cognitive decline in aging. One contributor to cognitive decline is the loss of blood-brain barrier integrity.”

“Related studies have found that oral bacteria colonize the brain and release toxins that disrupt the blood-brain barrier, impairing its function and increasing the risk of Alzheimer's disease.”

“Scientists find that visceral fat, a type of adipose tissue that produces high levels of inflammatory signals known as adipokines, impair learning and memory in mice by setting off an inflammatory cascade mediated by the release of IL-1 beta, which crosses the blood-brain barrier leading to chronic activation of microglia.”

“It has previously been shown that inflammatory molecules produced as a consequence of gut permeability can cross the blood-brain barrier and lead to anxiety and depression. Additionally, the vagal nerve connecting the gut to the brain may also be at play here.”

“Tissues with higher numbers of mitochondria (such as muscle, brain, heart, and nerves) tended to respond better to lower light doses. In contrast, tissues with lower mitochondrial activity (skin, tendon, and cartilage) responded better to higher light doses.”

“Poor gut barrier function may contribute to carotid atherosclerosis – a narrowing of the blood vessels that supply the brain – according to a new study. People with carotid atherosclerosis demonstrated increased markers of gut barrier damage and inflammation, both of which impair butyric acid uptake into the blood.”

“> "Cigarette smoking is one of the most compelling environmental risk factors linked to the development and worsening of MS," > Results showed that smokers with MS had a greater breakdown of the blood-brain barrier, had nearly 17 percent more brain lesions -- patches of inflammation in the sheath surrounding the nerve fibers that impair their function -- than nonsmokers with MS…”