Search results for genome

“In 2003, the Project completed its main objectives by sequencing 92 percent of the genome and fueling a rapid expansion in biomedical research. Dr. Church then advocated for more genomes to be sequenced enabling comparisons, fueling a positive feedback loop of DNA reading, writing, and new tool discovery.”

“As each new milestone in editing is surpassed, entirely new paradigms of what may be possible with genome engineering emerge. One example of mind-boggling applications that Dr. Church and his colleagues hope to develop: producing human cells with perfect viral resistance.”

“Telomeres are distinctive structures comprised of short, repetitive sequences of DNA present on the ends of chromosomes. They protect the genome from damage during regular cell division or under conditions of physiological or emotional stress.”

“Could cell therapies confer this total viral resistance in humans in the future? In this clip, Dr. George Church discusses how revolutionary technologies such as multiplex genome editing and genome writing could make this and other advances in human health possible.”

“Human activity continues to result in the loss of biodiversity, but synthetic biology offers a chance to restore plants, animals, and other life to ecosystems around the world. In this clip, Dr. George Church describes Genome Project-Write, its goals, and the technology fueling it.”

“In this FoundMyFitness solo episode excerpt, Dr. Rhonda Patrick uses Dr. Bruce Ames's triage theory to explain why marginal magnesium intake may matter long before a classic deficiency appears.”

“Dr. Steve Horvath, a professor of genetics and biostatistics at UCLA, has found a way to measure biological aging – a "clock" – based on the methylation pattern of an organism's genome.”

“Multiple age-related inputs can keep innate immune pathways active, including the senescence-associated secretory phenotype, mitochondrial damage and oxidative stress, debris released by injured cells, visceral adipose tissue inflammation, chronic infections, increased intestinal permeability, and dysbiosis.”

“This mitochondrial DNA is inherited from mother to child and originates in the oocyte (i.e., egg cell) prior to fertilization. Because mitochondria must also maintain a functional genome, they are also susceptible to damage from oxidative stress and radiation.”