Quercetin
“Quercetin and cardiovascular disease Quercetin and hypertension Hypertension, or high blood pressure, damages blood vessels. If untreated, the condition can lead to heart disease and stroke, two leading causes of death worldwide.”
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Quercetin is a plant-derived flavonol found in foods such as onions, apples, tea, berries, and lettuce, with reported antioxidant and anti-inflammatory activity across multiple organ systems. Human cardiovascular evidence is suggestive rather than definitive: a meta-analysis…
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“Quercetin and cardiovascular disease Quercetin and hypertension Hypertension, or high blood pressure, damages blood vessels. If untreated, the condition can lead to heart disease and stroke, two leading causes of death worldwide.”
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“It has been identified as a zinc ionophore which is a compound that can transport zinc ions across a cell membrane. In this clip, Dr. Rhonda Patrick discusses quercetin's identified antiviral activity against SARS-CoV-1 and its role in zinc transport.”
“Quercetin - a flavonol found in apples, onions, and other edible plants that exerts antioxidant, anti-inflammatory, and anti-aging properties across multiple organ systems. Resveratrol - a polyphenolic compound found in red grapes, peanuts, and other edible plants that demonstrates beneficial cardiovascular effects.”
“Flavonols (e.g., quercetin from tea, apples, and onions). Hydroxycinnamic acids (e.g., chlorogenic acids, abundant in coffee and many fruits and vegetables). Anthocyanins (blue/purple pigments found in fruits such as blueberries and chokeberries).”
“To learn more about quercetin, a plant compound with potential senolytic properties, read our overview article. To learn more about sirtuins, which lose function in the MiDAS phenotype, read our overview article.”
“Furthermore, in vitro studies suggest that quercetin, a plant-based dietary compound, facilitates the transport of zinc into cells. Foods that naturally contain quercetin include onions, green tea, apples, berries, Ginkgo biloba, St. John's wort, American elderberry, and buckwheat tea.”
“FOXO3 is activated by caloric restriction, intermittent fasting, and dietary components, such as EGCG, which is in green tea, and quercetin, which is in onions and apples. Heat stress, such as from using the sauna, also activates FOXO3.”
“These findings suggest that the antioxidant properties of quercetin decrease exercise produced ROS thereby blocking mitochondrial biogenesis. Additionally, the authors suggested that metabolites of quercetin may be influencing the production of oxidative damage.”
“A recent meta-analysis and systematic review suggests that quercetin may exert protective effects to reduce the risk of cardiovascular disease. Quercetin is a flavonol compound found in a wide variety of fruits and vegetables, including onions, apples, tea, and lettuce.”
“Taxifolin is a naturally occurring compound found in a variety of edible plants. Also known as dihydroquercetin, taxifolin is chemically related to quercetin. Evidence suggests that taxifolin exerts antioxidant, anti-inflammatory, and anticancer properties.”
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