FoundMyFitness library
Ranked by shared topics.
“Time-restricted eating exploits the body's innate 24-hour patterns – the genetically encoded molecular clocks present in every cell, from the complex (liver cells) to the simple (hair follicles) – and provides the body an essential downtime where it can focus on DNA and cellular repair and restoration rather than digestion.”
“Run the longevity report to learn more about genetic polymorphisms influencing the expression of FOXO Background FOX proteins are named for a gene found in fruit flies that causes the insects to have forked structures on their heads (providing the "F") and a particular group of specialized genes – known as a "box" (providing the "OX").”
“Multiple age-related inputs can keep innate immune pathways active, including the senescence-associated secretory phenotype, mitochondrial damage and oxidative stress, debris released by injured cells, visceral adipose tissue inflammation, chronic infections, increased intestinal permeability, and dysbiosis.”
“However, a study involving more than 2,500 mentally healthy older adults found that a higher daily dietary magnesium intake (at least 407 milligrams) was linked to better overall brain function, primarily among non-Hispanic white females with adequate vitamin D status, underscoring the interdependence of the two nutrients.”
“In a recent double-blind placebo-controlled trial involving 27 healthy older adults (average age, 62 years) with at least one risk factor for diabetes, each of the study participants engaged in three 45-minute aerobic exercise training sessions per week for 12 weeks using a treadmill, stationary cycle, or elliptical machine.”
“In an attempt to control for the healthy user bias (the possibility that people who take multivitamins may have better lifestyle habits than nonusers), the statistical analyses were adjusted for confounding factors like age, sex, education, alcohol and tobacco use, BMI, physical activity, diet quality, family history of cancer, and the use of other supplements.”
“Compared with no resistance training, 90–119 minutes per week was associated with a 13% lower rate of death from any cause, a 19% lower rate of cardiovascular death, and a 27% lower rate of neurological disease death after accounting for aerobic activity and other health and lifestyle factors.”
“Using isotope tracers that allowed them to distinguish NAD+ made directly from NR or NMN versus NAD made from nicotinamide, NR, or NMN, they found that a low oral dose of the precursors (50 milligrams per kilogram body weight, mg/kg/bw) produced very low levels of NAD+ made directly from NR and NMN in the liver but not in other tissues.”
“For example, a large, population-based study that drew data from more than 170,000 men and women between the ages of 30 and 75 years showed that animal protein intake was associated with increased death rates only when the participants had at least one unhealthy lifestyle risk factor such as smoking, heavy alcohol consumption, physical inactivity, or being overweight or obese.”
“In a study involving diet-induced diabetic mice, injection of 500 milligrams per kilogram of body weight (mg/kg/bw) of nicotinamide mononucleotide administered for seven days enhanced insulin sensitivity and improved glucose intolerance compared to that observed among mice not given nicotinamide mononucleotide.”