Related Episodes for Does Alcohol Explain Longevity in Blue Zones?

“There is so much to say when we talk about the NRF2 pathway and isothiocyanates like sulforaphane that we had to pack it into 47 minutes and break it into a few key sections. Key sections: For a more in-depth breakdown click the timeline link at the top of this page!”

“A systematic review and meta-analysis found no evidence that one time of day produces universally better improvements in health or performance, although gains can be larger when the time of training matches the time of testing.”

“Uric acid adds another long-range signal. In the Swedish AMORIS cohort, 1,224 people who reached age 100 tended to have lower midlife glucose, creatinine, and uric acid than peers who did not become centenarians.”

“Older adults can have anabolic resistance and may need more protein per meal to reach a leucine threshold; Dr. Schoenfeld discusses roughly 2–3 grams of leucine as a flexible estimate, not a hard cutoff or a reason everyone needs isolated leucine.”

“A national survey analysis estimated 2.6% severe deficiency, 22% moderate deficiency, and 40.9% insufficiency among US adults, although prevalence changes with the threshold used. These categories should remain distinct because insufficiency is not the same as clinical deficiency.”

“A 2025 meta-analysis found improved quality of life, no clear overall change in ejection fraction, and a borderline improvement in New York Heart Association functional class across a small set of trials.”

“A standard multivitamin may support selected older adults by filling dietary gaps, and population surveys show that many people consume less than estimated requirements for nutrients such as magnesium, calcium, and vitamins A and C.”

“Dr. Patrick also distinguishes general-population evidence from people with diabetes or insulin resistance, where some observational studies report different risk patterns and residual confounding remains substantial.”

“In this clip from Q&A #68, Dr. Rhonda Patrick compares stearic, palmitic, myristic, and lauric acids and explains why chocolate, cheese, butter, and coconut oil can produce different lipid responses.”