Related Episodes for Why we need a blood-brain barrier to prevent neurotoxicity — can we prevent fibrinogen deposition? | Axel Montagne Ph.D.

“Dr. Patrick explains that she uses zinc lozenges only during exposure or the earliest signs of illness, often totaling roughly 80 to 100 milligrams per day for a short period. Small randomized zinc-acetate lozenge trials have produced mixed results, with one reporting a shorter cold and another finding no faster recovery with more adverse effects.”

“Her practical message is to reduce the frequency and size of large glucose exposures. Foods with intact fiber, protein, and minimally processed carbohydrates digest more slowly than refined added sugar, while regular exercise gives skeletal muscle a large destination for circulating glucose.”

“In animal studies, high doses of magnesium in the form of magnesium L-threonate have been shown to cross the blood-brain barrier readily and coincide with improvements in cognitive function.”

In this clip, Dr. Griffiths talks about the effect of dose on psilocybin mystical experiences and ‘bad trips’.

“In this clip from Dr. Rhonda Patrick's appearance on Modern Wisdom, she explains how a large post-meal glucose rise and fall can contribute to the sluggish feeling people call brain fog. Food order offers one practical lever.”

“The human body can convert some ALA into EPA and then to DHA, but the efficiency of the process varies between individuals. In this clip, Rich Roll and Dr. Rhonda Patrick discuss how those on a vegan diet can determine whether they are getting enough omega-3 fatty acids.”

“The aggregate of these exposures is referred to as the "exposome" – the totality of non-genetic exposures that a person experiences during a lifetime – and includes nutritional, environmental, microbial, financial, and emotional factors.”

“Aging in tumor tissue is markedly accelerated, however – an indicator of the perturbed metabolic and growth processes observed in cancer. In this clip, Dr. Steve Horvath discusses correlations between epigenetic aging and age-related chronic diseases.”

“Contrary to the traditional view of lactate as a metabolic waste product, it is now recognized for its critical role in brain health. Elevated lactate levels after vigorous exercise are linked to improved executive function, hinting at its potential protective benefits against neurodegenerative diseases.”

“Dr. Patrick also describes a proposed anti-metastatic mechanism: faster blood flow during vigorous exercise increases shear forces on circulating tumor cells, the cells that have left a primary tumor and entered the bloodstream.”