Related Episodes for Bruce Ames on Triage Theory, Longevity Vitamins & Micronutrients

“Early biomarkers of vascular dysfunction, such as soluble platelet-derived growth factor receptor-beta (sPDGFR-β), can help identify individuals at risk for developing Alzheimer's disease. These biomarkers are being validated on high-throughput platforms for large-scale testing.”

“Because of alcohol’s effect on other organs and the evidence that any dose of alcohol appears to elevate cancer risk, Dr. Huberman thinks that zero to two drinks per week represents a “safe zone” as long as you’re of age, not pregnant, and not an alcoholic.”

“However, the ability to translate data from non-human animals to humans can be limited and the use of laboratory animals can raise ethical concerns. In this clip, Dr. George Church describes the pros and cons of animal research and how we could move beyond its use with advanced technologies.”

“For people whose ApoB rises on a high-saturated-fat diet, replacing butter, cheese, fatty red meat, coconut oil, and palm oil with olive oil, avocado, nuts, and fish is a practical experiment to review with a clinician.”

“Consensus evidence supports ApoB as a causal risk factor, but Dr. Attia’s proposed 10–30 mg/dL physiological range and treatment targets are attributed opinions, not universal guideline targets. Diet can change ApoB through several pathways.”

“Dr. Krauss explains how some people might be inappropriately prescribed statins while other people should be taking statins. In addition, his current research is investigating whether statins can increase the risk of diabetes, especially for women.”

“Dr. Aubrey de Grey is a biomedical gerontologist and the founder of the SENS Research Foundation which aims to find technologies that can repair the various types of damage that occur during the aging process. Learn more about Dr. Aubrey De Grey SENS Research Foundation.”

“Premenopausal females have much lower rates of cardiovascular disease than similarly aged males because of the protective effects of estrogen, but after menopause, there's not much of a difference, and cardiometabolic risk factors actually worsen in females during the menopause transition, indicating this may be a crucial time for exercise intervention to protect the cardiovascular system.”

“A common feature of heart disease is arrhythmia, an irregular heartbeat. Interestingly, research in fruit flies has shown that unhealthy lifestyle behaviors, such as poor sleep and diet, increase the risk of developing arrhythmias.”

“- Practical details like temperature and duration of sauna use, the difference between a dry, wet and infrared sauna, sauna timing, as well as other forms of heat stress such as steam showers, hot baths, and hot yoga.”