Related Episodes for DEBUNKED: 2/3rds of Cancer "Just Bad Luck"

“In this clip from Q&A #70, Dr. Rhonda Patrick organizes cancer prevention around the largest modifiable foundations: avoid tobacco, maintain a healthy body composition, and stay physically active.”

“In this FoundMyFitness interview clip, Dr. Peter Attia explains that early detection can reduce the burden of disease available to mutate and evade treatment, but screening carries financial, procedural, and false-positive harms.”

“Moreover, taking mega doses (i.e. 400 IU/day) of alpha tocopherol has the unintended side-effect of actually depleting tissue levels of another important form of vitamin E that plays an anti-inflammatory role, known as gamma tocopherol.”

“Patients assigned to supervised exercise during neoadjuvant chemoradiation, followed by continued activity before surgery, were more likely to achieve a complete or near-complete pathological response than those receiving usual care.”

“IGF-1 participates in a complex pathway known as the growth hormone/IGF-1 axis, where it exerts its role to accelerate aging. In this clip, Dr. Valter Longo explains how certain macronutrients influence the insulin/IGF-1/growth hormone axis to modulate aging in many cell types.”

“A large dose-response meta-analysis of prospective studies found that greater non-occupational physical activity was associated with lower risks of total cancer and several site-specific cancers, with meaningful benefits appearing below current guideline levels.”

“Osimertinib, for example, improved five-year survival among patients with resected EGFR-mutated lung cancer, while CAR-T therapy has produced durable remissions in some children and young adults with relapsed or refractory B-cell acute lymphoblastic leukemia.”

“Insulin-like growth factor 1 (IGF-1) plays a role during childhood for growth and continues later in life to have anabolic and neurotrophic effects. IGF-1 is also implicated in contributing to aging and enhancing the growth of cancer after it has been initiated.”

“A healthy immune system allows the body to fight bacterial and viral infections, as well as aberrant cells, which, left unchecked can progress to cancer. Insulin-like growth factor 1 (IGF-1) has some beneficial functions but is also known to promote the growth of existing cancer cells.”

“Whether metformin reduces the risk of cancer in healthy people remains to be seen. In this clip, Dr. Rhonda Patrick describes the relationship between metformin and cancer incidence and the relevance for those with type 2 diabetes.”