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Related Episodes for Intermittent fasting is a meaningless term | Valter Longo

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Aliquot #96: Thermal Stress, Part I: The Science Behind Heat Stress and its Positive Effects on Health

Oct 22, 2023

Hormesis is a compensatory defense response to a stressor that conditions the body against future stressors. Heat exposure – from sauna use, hot tubs, or eve...

aliquot aging metabolism heat stress
Duration: 43m
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"Type 3 diabetes" — could blood-brain barrier breakdown be the cause? | Axel Montagne, Ph.D.

Mar 25, 2023

“Animal studies indicate that omega-3 deficiency may also reduce GLUT1 transporters in the brain. Other studies suggest that omega-3 supplementation reduces VCAM1 levels – a protein elevated with normal aging, which could be related to the breakdown of the blood-brain barrier.”

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Does animal research help us understand human aging? │ Dr. George Church

Sep 2, 2022

“However, the ability to translate data from non-human animals to humans can be limited and the use of laboratory animals can raise ethical concerns. In this clip, Dr. George Church describes the pros and cons of animal research and how we could move beyond its use with advanced technologies.”

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Anti-catabolic effects of heat | Dr. Stuart Phillips

Jul 10, 2022

“The mechanisms that drive the effects of sauna bathing include activation of heat shock proteins and pro- and anti-inflammatory cytokines; decreased blood pressure and arterial stiffness; and multiple improvements in cardiovascular function.”

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Antihypertensive drugs and COVID-19

Jun 21, 2020

“Some researchers have hypothesized that since antihypertensive drugs like ACE inhibitors and angiotensin II receptor blockers, or ARBs, increase ACE2, they might alter the risk of severe COVID-19 disease.”

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APOE 3/4 and APOB and their influence on Alzheimer’s and cardiovascular disease | Peter Attia

Feb 11, 2020

“Approximately 25 percent of people living in the United States carry a genetic variant of this lipoprotein called APOE4, which is associated with higher circulating levels of LDL cholesterol and an increased risk for Alzheimer's disease.”

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APOE4 gene and associated risk for Alzheimer's disease | Dale Bredesen

Jul 12, 2019

“Approximately 25 percent of people in the United States – roughly 75 million people – carry a genetic variant of this lipoprotein called APOE4, which is associated with higher circulating levels of LDL cholesterol and an increased risk for Alzheimer's disease.”

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Are statins over-prescribed? | Ronald Krauss

Apr 3, 2022

“Dr. Krauss explains how some people might be inappropriately prescribed statins while other people should be taking statins. In addition, his current research is investigating whether statins can increase the risk of diabetes, especially for women.”

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Dr. Aubrey de Grey and Dr. Rhonda Patrick Talk Aging

Aug 13, 2015

“Dr. Aubrey de Grey is a biomedical gerontologist and the founder of the SENS Research Foundation which aims to find technologies that can repair the various types of damage that occur during the aging process. Learn more about Dr. Aubrey De Grey SENS Research Foundation.”

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How Exercise Prevents & Reverses Heart Aging | Dr. Benjamin Levine

May 29, 2024

“Premenopausal females have much lower rates of cardiovascular disease than similarly aged males because of the protective effects of estrogen, but after menopause, there's not much of a difference, and cardiometabolic risk factors actually worsen in females during the menopause transition, indicating this may be a crucial time for exercise intervention to protect the cardiovascular system.”

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