Related Episodes for Exercise-induced autophagy and its role in preventing diabetes | Guido Kroemer

“Although whole-body hyperthermia and sauna use share some similarities, whole-body hyperthermia sessions are typically longer (an hour or more) and the participant's head is spared (often kept cool with ice or cool cloths), prolonging the participant's tolerance to the intense heat.”

“The Kuopio Ischemic Heart Disease Risk Factor Study, an ongoing prospective population-based cohort study of health outcomes in more than 2,300 middle-aged men from eastern Finland, identified strong, dose-dependent links between sauna use and reduced death and disease.”

“A staggering 60% of all calories Americans consume come from ultra-processed foods that fail to induce proper satiety, remain cheaper than whole foods, and hijack our dopamine reward pathways, pushing us to overeat, incentivizing unhealthy food choices, and reinforcing addictive eating behaviors.”

“When most people think about certain lifestyle factors that affect insulin sensitivity and blood glucose levels, they think about macronutrient composition, or calories, or fasting, or exercise (and lack of), but they don’t often think about sleep.”

“The hydrolytic conversion of glucoraphanin to sulforaphane requires myrosinase, an enzyme co-located within the leaves, stems, and other components of the plants in which it is found. In humans, myrosinase-producing gut bacteria can convert unhydrolyzed glucosinolates to their cognate isothiocyanates, as well.”

“In a placebo-controlled study of eight healthy adults, adrenaline infusion lowered plasma magnesium, and levels had not recovered one hour later. Investigators proposed a shift into cells after beta-adrenergic stimulation; the study did not measure cortisol, urinary loss, total-body depletion, or clinical deficiency.”

“During the peak phase, participants sometimes completed two interval sessions per week, while the longer maintenance phase generally used one interval session alongside continuous endurance work and strength training.”

Dr. Rhonda Patrick, Dr. Darya Rose, and Kevin Rose discuss turmeric's ability to increase detoxification enzymes through hormesis.

“Since then, countless studies have tested Pauling's theories about vitamin C, colds, and cancer (and many others), and a substantial body of evidence has emerged, identifying critical roles for vitamin C in immune function, cardiovascular and respiratory health, cognitive development and preservation, and many other aspects of human health.”

“A meta-analysis restricted to direct regional measures from MRI, CT, or ultrasound found a very small average hypertrophy benefit when creatine was combined with resistance training, with uncertainty around the pooled estimate and variation across sites and populations.”