Related Episodes for How Micronutrients & Exercise Ameliorate Aging | Dr. Rhonda Patrick

“For people whose ApoB rises on a high-saturated-fat diet, replacing butter, cheese, fatty red meat, coconut oil, and palm oil with olive oil, avocado, nuts, and fish is a practical experiment to review with a clinician.”

“However, she considers the amounts in its proprietary superfood, extract, and probiotic blends too small to justify expecting the broader benefits implied by those categories. She presents this as her assessment of the product label.”

“In this clip, Dr. Ruth Patterson discusses how healthful choices, such as even modest weight loss, can have beneficial effects that reduce the risk of breast cancer and a variety of other diseases.”

Alcohol, in particular, can have negative effects on a breastfed infant, including altered sleep patterns, decreased milk intake, and impaired motor development (https://link.springer.com/article/10.1007/s00216-010-3681-0), among others.

“Additionally, we also discuss the important role magnesium plays in preventing random mutations. "Men with the highest quartile of magnesium levels have a 40% decrease in all-cause mortality and a 50% decrease in deaths from cancer.".”

“Other hormetic responses to cold exposure include increased production of PGC1-alpha, a protein that promotes mitochondrial biogenesis, the production of new, healthy mitochondria, and the activation of brown fat – a phenomenon once thought to occur only in newborns, but now known to occur in adults, especially after cold exposure.”

“Perhaps the most clear-cut examples of cryotherapy’s beneficial effects are observed in the brain, where levels of the hormone and neurotransmitter norepinephrine – responsible for vigilance, attention, focus, and positive mood – increase markedly when the body is exposed to extreme cold.”

“For example, while vitamin C acts primarily as an antioxidant at physiological concentrations of approximately 50 micromoles per liter, pharmacologic doses of intravenous vitamin C greater than 1 gram generate hydrogen peroxide, a type of reactive oxygen species produced by neutrophils to destroy pathogens such as viruses.”

“Dr. Rhonda Patrick discusses the differences between different forms of DHA in terms of bioavailability and transport into different cells. She talks about why a specific type of DHA (DHA in phosphatidylcholine) is more readily transported into the brain because it forms DHA-lysophsophatidylcholine.”

“Dr. Patrick explains that she uses zinc lozenges only during exposure or the earliest signs of illness, often totaling roughly 80 to 100 milligrams per day for a short period. Small randomized zinc-acetate lozenge trials have produced mixed results, with one reporting a shorter cold and another finding no faster recovery with more adverse effects.”