In this clip, Dr. Roger Seheult describes how a diminished interferon response drives poor outcomes in COVID-19.
Dr. Valter Longo explains the difference between caloric restriction and periodic fasting and highlights the importance of refeeding after a fast.
In this clip, Dr. Patrick explains how intense exercise beneficially alters tryptophan and kynurenine metabolism in a way that may benefit depression.
In this clip, Dr. Peter Attia explains his position on the relationship between insulin resistance and Alzheimer’s disease risk.
In this clip, Dr. Stuart Phillips discusses his concerns regarding the current protein recommended dietary allowances.
In this clip, Dr. Rhonda Patrick discusses how heat can be used to increase muscle strength and counteract muscle wasting.
Dr. Matthew Walker describes the role that sleep plays in modulating the accumulation of amyloid-beta accumulation in the brain.
In this clip, Dr. Rhonda Patrick describes how the physiological effects observed during sauna use are comparable to those that occur during physical exercise.
Scientists have observed that the epigenetic clock of transplanted cells and their descendant lineages synchronize with the donor rather than the recipient, a fascinating phenomenon that offers promise for the idea of rejuvenation in humans.
Dr. Dale Bredesen describes the risks associated with APOE4 and identifies strategies for mitigating that risk.
In this clip, Dr. Rhonda Patrick describes how sauna use activates the Salvinorin A pathway, potentially ameliorating symptoms of depression and opioid addiction.
Dr. Jed Fahey describes how sulforaphane was discovered, how it is produced in plants, and the mechanisms by which it produces health effects in humans.
In this clip, Dr. Dominic D'Agostino describes different approaches that allow the ketogenic diet to be more accessible.
In this clip, Dr. Dominic D'Agostino describes how nutritional ketosis may support the treatment of neurodegenerative and other brain disorders.
In this clip, Dr. Peter Attia and Dr. Rhonda Patrick discuss the unique dietary and lifestyle considerations for carriers of the APOE4 gene variant.