Dr. Charles Raison describes how the body has evolved to employ some of the same physiological mechanisms in depression and physical illnesses.
Dr. Charles Raison describes strategies that have evolved to offset the risks associated with eating, such as inflammation and the antibiotic effects of hyperthermia.
Dr. Charles Raison describes how whole-body hyperthermia has the potential for real-world clinical efficacy as a tool in the fight against major depression.
Dr. Charles Raison explains that taking non-steroidal anti-inflammatory agents or high dose antioxidants may block some of the benefits of exercise.
Dr. Charles Raison explains the relationship between thermoregulatory dysfunction and how periodic exposure to high heat may aid with treating depression and schizophrenia.
Dr. Charles Raison highlights how ancient practices such as heat exposure, long-distance running and fasting may promote well-being in the modern world.
Dr. Charles Raison discusses how psychedelic substances like psilocybin, which induce transcendent trance-like states may be useful in the treatment of depression.
Dr. Elissa Epel discusses potential concerns about supplementation and describes some of the studies that demonstrate the links between healthy lifestyle behaviors.
Dr. Elissa Epel identifies several biohacks that show promise as strategies to reduce stress and lengthen telomeres.
Dr. Rhonda Patrick describes the effects of endogenous ketones on fat metabolism during a fast.
Dr. Rhonda Patrick provides advice on how to break a fast.
Dr. Rhonda Patrick discusses when electrolyte replenishment might be necessary.
Dr. Rhonda Patrick describes the dual nature of biochemical pathways involved in aging and explains how exercise tips the balance toward its beneficial properties.
Dr. Rhonda Patrick discusses the circumstances under which eating prior to exercise is beneficial versus detrimental.
Dr. Rhonda Patrick describes some of the different types of fasting and identifies the advantages associated with each.