Post-prandial inflammation and fasting as a method to counteract it. | Charles Raison

Parent Episode: Dr. Charles Raison on Depression, the Immune-Brain Interface & Whole-Body Hyperthermia

Eating food is hard on the gut as it involves the ingestion of foreign substances. The gut lining becomes slightly compromised with each meal, and the immune system is activated. Humans may have evolved strategies to counteract these risks. For example, the inflammatory response that is triggered after a meal contributes to a less hospitable environment for foodborne pathogens. Furthermore, diet-induced thermogenesis, a rise in body temperature that occurs after eating, may also serve an antibiotic role. Periods of fasting have a powerful anti-inflammatory effect. In this clip, Dr. Charles Raison describes strategies that have evolved to offset the risks associated with eating, such as inflammation and the antibiotic effects of hyperthermia.

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