Related Episodes for Two-decade phytochemical expert Dr. Jed Fahey responds to carnivore doctor’s rant | Jed Fahey

“00:20:21 - Some of the key blood-based biomarkers that are useful for tracking and projecting future cognitive health, including: homocysteine (<7μml/L preferred), which Dr. Bredesen indicates may be a mediator of cerebral atrophy, and also fasting insulin (<5% preferred), hemoglobin A1c, fasting glucose, vitamin D, and a number of other hormones relevant for trophic support.”

“However, vegans and vegetarians frequently have higher levels of other micronutrients, such as vitamins C and E. Getting the required micronutrients is essential for maintaining optimal health when following a vegan diet.”

“Dr. Rhonda Patrick discusses the differences between different forms of DHA in terms of bioavailability and transport into different cells. She talks about why a specific type of DHA (DHA in phosphatidylcholine) is more readily transported into the brain because it forms DHA-lysophsophatidylcholine.”

“The impact of the ketogenic diet on gut bacteria has not been actively studied. In animal models high-fat diets are thought to provoke the release of endotoxin from bacterial cell membranes resulting in negative health consequences. In this clip, Dr. Dominic D'Agostino and Dr. Rhonda Patrick discuss the ketogenic diet and its implications for gut health.”

“Moreover, taking mega doses (i.e. 400 IU/day) of alpha tocopherol has the unintended side-effect of actually depleting tissue levels of another important form of vitamin E that plays an anti-inflammatory role, known as gamma tocopherol.”

“For example, if basic research reveals that a particular diet is best for longevity, yet no long-lived populations around the world eat this way, then one may choose to be cautious about this diet.”

“00:44:53 - How marine omega-3 fatty acids EPA and DHA may be one of the safest supplements to delay telomere attrition, with each 1-standard deviation increase in levels associated with a 32% reduction in the odds of telomere shortening and how one four-month double-blinded supplementation study showed that omega-3 could even lengthen telomeres.”

“Conventional health advice, such as healthy eating, physical activity, and education level are linked with slowed epigenetic aging, albeit weakly, and obesity, sleep deprivation, and smoking are linked with accelerated epigenetic aging.”

“However, exercising while taking a non-steroidal anti-inflammatory agent (NSAID) may blunt the initial rush of acute inflammation and negate some of the long term health effects of exercise.”

“Dr. Patrick explains some of the early evidence that suggests the value prolonged fasting (48+ hours) may have from the standpoint of tissue rejuvenation and healthspan maintenance, as well as relevance for other more specific conditions.”