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Polyphenol-Rich Diets and Brain Aging
“The participants who reported consuming the shake more than 3 times per week and green tea 2 or more times per week had the greatest improvements in glucose control biomarkers (e.g., fasting glucose and HbA1c).”
Polyphenols
“The other half consumed their normal diet with no substitutions. After eight weeks, the two groups switched to the opposite diet. The polyphenol-rich foods included berries, blood oranges (and their juice), pomegranate juice, green tea, apples, and dark chocolate.”
Cocoa flavonoids (chocolate)
“Related resources Topic articles Polyphenols - a broad family of bioactive plant compounds that exert a wide range of health effects in humans, including notable compounds like anthocyanins (found in berries), EGCG (epigallocatechin gallate, found in green tea), and many more.”
Adding vitamin C to green tea increases the bioavailability of the antioxidants present in the green tea.
“Some evidence suggests that adding vitamin C to green tea might increase the bioavailability of the catechins present in green tea. Consumers of green tea commonly add milk, lemon, or other substances to their tea.”
Small vessel disease
“Polyphenols from foods such as berries, greens, and tea inhibit the NFkB inflammatory pathway and, therefore, may reduce Parkinson's disease risk. In studies with mice, polyphenol treatments reduce inflammation and oxidative stress and protect dopaminergic neurons.”
FOXO
“FOXO3 is activated by caloric restriction, intermittent fasting, and dietary components, such as EGCG, which is in green tea, and quercetin, which is in onions and apples. Heat stress, such as from using the sauna, also activates FOXO3.”
Individuals who drank green tea, oolong tea, or black tea 4x/week for 25 yrs had more efficient brain connections in certain brain regions.
“Individuals who drank green tea, oolong tea, or black tea 4x/week for 25 yrs had more efficient brain connections in certain brain regions compared to non-tea drinkers. The same research group previously found that tea consumption was linked to a 50% reduction in cognitive decline.”
Intestinal permeability
“A diet rich in polyphenols, especially those from cocoa and green tea, may reduce the risk of intestinal permeability in older adults. These benefits may arise from the compounds' capacity to support populations of butyrate-producing bacteria in the gut.”
A green tea polyphenol (EGCG) attenuated the progression of abdominal aortic aneurysm in a rat model. (2016)
“In the study, the team treated rats with enzymes that induce abdominal aortic aneurysm, and found that the condition developed less in rats that drank green tea polyphenol. They also saw less inflammation and more elastin production, protecting the artery from rupture.”
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