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Schizophrenia is linked to multiple biological domains rather than a single pathway. Vitamin D may influence neurodevelopment through dopamine-producing neurons, while low prenatal vitamin D has been associated with greater later risk; one estimate suggested this…

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Based on available source text from 9 of the first 10 results.

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Thermoregulation dysfunction and association with depression and schizophrenia. | Charles Raison

Aug 28, 2019

People experiencing depression or schizophrenia tend to have impaired thermoregulation, causing difficulties with sweating and cooling themselves off. Using heat exposure, investigators were able to sensitize pathways important to thermoregulatory cooling (https://www.ncbi.nlm.nih.gov/pubmed/27172277) that also affect brain regions implicated in the regulation of mood.

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Berberine

Jun 6, 2025

“Findings from a randomized controlled trial demonstrate the efficacy of berberine supplementation in preventing weight gain and metabolic syndrome among patients taking antipsychotic medications, which cause predictable weight gain, glucose dysfunction, and dyslipidemia…”

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