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Science Digest

Genetic evidence ties higher blood caffeine levels to lower body fat and reduced type 2 diabetes risk.

Jan 23, 2026

“Slower caffeine breakdown keeps circulating levels elevated for longer periods, which may increase energy expenditure through caffeine-induced thermogenesis and fat oxidation. Experimental work suggests caffeine enhances mitochondrial activity, increases sympathetic nervous system signaling, and shifts brown fat tissue toward a more metabolically active state.”

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