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Omega-3 phospholipid DHA and supplementation | Rhonda Patrick
“This clip originates from an interview recorded on the Kevin Rose Show, which you can click here to download the full version of. Docosahexaenoic acid (DHA), an essential omega-3 fatty acid, promotes health and development of the brain.”
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Exacerbation of traumatic brain injury in APOE4 carriers | Peter Attia
“Traumatic brain injury (TBI) results from damage caused by a sudden blow, penetrating injury, or lack of oxygen. A TBI may increase the risk of developing Alzheimer’s disease and other brain disorders, especially in people carrying the APOE4 gene. In this clip, Dr. Peter Attia stresses the further risks of head trauma for those with the APOE4 gene variant.”
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The connection between Alzheimer’s disease and insulin resistance | Peter Attia
“Convincing animal data and preliminary research in patients with early cognitive decline have shown positive outcomes using strategies to overcome insulin resistance. In this clip, Dr. Peter Attia explains his position on the relationship between insulin resistance and Alzheimer’s disease risk.”
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Metformin may mimic caloric restriction and intermittent fasting | Dominic D'Agostino
“The body perceives these interventions as stressors and then adapts, ultimately developing metabolic flexibility. Dr. D'Agostino proposes that metabolic interventions, such as restricting calories and entering ketosis, for example, may provide additional benefits when practiced cyclically.”
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How changes in cellular identity and stem cell differentiation affect epigenetic age
“Methyl patterns are crucial for a cell's maintenance of identity. As techniques are developed to differentiate and transdifferentiate cells from one cell type, such as a fibroblast, into another, such as a neuron, interesting patterns of effects on epigenetic age are revealed.”
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How Exercise and Sleep Support Immune Function With Age
“A systematic review in older adults linked Mediterranean dietary patterns with lower inflammatory markers, while a meta-analysis of randomized trials found that vitamin D supplementation reduced acute respiratory infection risk overall, with the strongest protection among people who were very deficient and received regular doses.”
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