Search results for genetics

“The principal enzymes involved in phase 1 metabolism of berberine are the cytochrome P450, or CYP, enzymes, specifically CYP2D6. Genetic polymorphisms that influence the expression of CYP2D6 subsequently influence berberine metabolism and should be taken into consideration when determining dose.”

“Both the age at cannabis use onset and insomnia outcomes were strongly shaped by inherited factors. The same genetic influences contributed to both traits, indicating shared genetic liability rather than environmental overlap.”

“Clinicians have regularly observed that their patients' insulin sensitivity worsens in the evening hours. Genetic studies have revealed that carriers of a variant of the melatonin receptor gene (MTNR1B) are more likely to have obesity or diabetes.”

“- Axel Montagne, Ph.D. A variant of the APOE gene called APOE4 is the primary genetic risk factor for late-onset Alzheimer's disease. Carrying one copy of APOE4 increases a person's Alzheimer's disease risk two- to threefold; carrying two copies increases a person's risk as much as 15-fold.”

“Sickle cell disease causes red blood cells to become deformed which can clump together to block the flow of blood around the body. This can cause intense pain, organ damage and can be fatal. After 15 months the boy has no sign of the disease.”

“From the article: Data from several genome-wide association studies were used to gauge genetic associations to lifestyle and cardiometabolic risk factors. [...] According to the analysis: -A genetic predisposition for insomnia was associated with a 24% increased risk for intracranial aneurysm and aneurysmal subarachnoid hemorrhage.”

“01:48:50 - Genetic variants in the vasopressin receptor gene influence pair bonding behavior in humans. Study. 01:53:05 - When female mice are deprived of cuddling, they become more promiscuous.”

“However, coffee is also rich in other bioactive compounds, including polyphenols, alkaloids, and others – many of which exert potent neuroprotective effects. While some forms of Parkinson's disease are genetic, most cases involve a complex interaction between genetic and environmental risk factors.”

“The investigators determined each participant's genetic propensity for developing depression – referred to as a polygenic risk score – and tracked air quality near the participants' homes. Participants completed various mental tasks while undergoing brain scans.”