Opioid painkillers, the most common prescribed drug for cancer pain, caused cancer cells to metastasize 20x faster.
“It is believed that this effect is caused by enhancing the growth of new blood vessels to the tumors, something called angiogenesis.”
The body’s endocannabinoid system regulates communication between the immune system and gut microbiota.
“Previous research has demonstrated that some strains of bacteria that produce SCFAs modulate the number of cannabinoid and opioid receptors in the gut. A dysregulated endocannabinoid system and gut microbiota may increase the risk of inflammatory bowel disease, irritable bowel syndrome, and obesity; however, exercise may improve microbiota and gut health.”
Aliquot #37: Lifestyle interventions for depression and anxiety, part 2 (adding to aliquot #8)
“Online resources that combine healthful practices and feedback may be beneficial for some people with depression but tapping into the benefits of less modern practices may be beneficial, too. Ancient practices, such as heat exposure, long-distance running, and fasting may promote mental well-being.”
Aliquot #35: Sauna use mimics the physiological effects of exercise
“As a result, sauna use is associated with lower risk of cardiovascular and neurodegenerative diseases. The mechanisms that drive these effects are likely due to increased heat shock proteins and metabolic and hormonal changes that accompany exercise and sauna use.”
Aliquot #96: Thermal Stress, Part I: The Science Behind Heat Stress and its Positive Effects on Health
Hormesis is a compensatory defense response to a stressor that conditions the body against future stressors. Heat exposure – from sauna use, hot tubs, or eve...
Episode
Dr. Eran Elinav: Microbiome Insights into Personalized Response to Diet, Obesity, and Leaky Gut
“Conversely, omega-3 fatty acids exert dramatic effects on the gut microbiome, which in turn elicits a range of beneficial responses, from enhanced immune function to reduced opioid-seeking behavior to improved mood, and many others.”
Episode
Roland Griffiths, Ph.D. on Psilocybin, Psychedelic Therapies & Mystical Experiences
“Dr. Roland Griffiths is a clinical pharmacologist at Johns Hopkins and one of the world's foremost researchers on the psychedelic compound psilocybin. Learn more about Dr. Roland R. Griffiths Johns Hopkins Profile - Roland R. Griffiths. List of Publications.”
Episode
The Truth About Alcohol: Risks, Benefits, and Everything In-Between | Dr. Rhonda Patrick
“While there’s no “alcoholism gene,” several gene variants have been associated with this condition. For example, people with one variant of the mu-opioid receptor (which is involved in the brain’s reward circuitry) experience a large dopamine increase when they consume alcohol.”
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