Search results for blood-brain barrier

“Another mechanism is the leaking of fatty acids from fatty acids, triggering toll-like receptors through the recognition of damage-associated molecular patterns (DAMPs). (See "obesity" section of toll-like receptor article.) Furthermore, LPS challenge in animal studies induces microglia in the brain to attack and damage the blood-brain barrier.”

“A phase 1 clinical trial shows that ultrasound can be used to safely open up a region of the blood-brain barrier for 24 hrs in patients with Alzheimer's disease. Previously, ultrasound was shown to restore memory function of 75% of mice that were treated.”

“In a mouse model of the disease, oral berberine administration (30 mg/kg/bw per day) reduced several of the pathological hallmarks associated with MS, including blood-brain barrier permeability and factors that drive the degradation of myelin.”

“Blood-brain barrier - Another membranous barrier in the body that loses its integrity with age. Increased microbial toxins in the blood because of increased intestinal permeability is a source of stress for the blood-brain barrier, injuring neurons and promoting disease.”

“From the article: > This exercise significantly reduced age-related pericyte loss in the brain cortex and improved other indicators of dysfunction of the vascular system and blood-brain barrier.”

“In an observational study involving more than 1,300 women between the ages of 65 and 80 years who were dementia-free at the time of enrollment, investigators measured omega-3 fatty acid concentrations in the women's red blood cells and white matter volumes in the women's brains.”

“In this FoundMyFitness episode excerpt, Dr. Rhonda Patrick explains that lactate crosses the blood-brain barrier through monocarboxylate transporters. Within the brain, glycolytic astrocytes produce lactate that neurons can import and use as fuel.”

“A common type of fungus, Candida albicans, was shown to cross the blood-brain barrier and trigger an inflammatory response in the brain that results in memory impairment (mouse study).”

“Disruption of brain DHA transport via the MFSD2A transporter causes blood-brain barrier breakdown. Furthermore, where we lose pericytes - which are important for dementia prevention - overlaps with the loss of DHA transporters.”

“Air pollution leaves a biological fingerprint on our lungs, our blood vessels, and even our brains, eroding the body's defenses, triggering inflammation, weakening the blood-brain barrier, and accelerating cognitive decline.”