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Effects of excessive caloric restriction on muscle mass and the brain | Dr. Mark Mattson
“Maintaining muscle mass is essential for health, but muscle mass decreases markedly with aging, compromising overall fitness and contributing to frailty, disability, and falls. Animal models demonstrate that intermittent fasting is generally beneficial for maintaining muscle mass, but in some disease states, such as ALS, or Lou Gehrig's disease, it can be detrimental.”