Menopause
The menopause transition, its hormonal effects on bone health and metabolism, and strategies for healthy aging.
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Menopause is a hormonal transition associated with changes in bone health, metabolism, sleep, body composition, and healthy aging. Visceral fat tends to rise during the transition as hormonal changes interact with age, activity, sleep, diet, and…
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The menopause transition, its hormonal effects on bone health and metabolism, and strategies for healthy aging.
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Drs. Levine and Patrick discuss how and why individuals age at different rates and how menopause & obesity may increase an individual's rate of aging.
“Information on calculating DNAm age using Horvath's method is freely available. "Using data from more than 2,300 adults, GrimAge accurately predicted time-to-death, time-to-coronary heart disease, time-to-cancer, and age-at-menopause".”
Q&A
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
“Instead, the findings strengthen the case for a complete program: aerobic training directly develops cardiorespiratory fitness, while resistance training supports muscle, bone, physical function, and potentially blood-pressure and autonomic regulation after menopause.”
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“Visceral fat also tends to rise during the menopause transition as hormonal changes interact with age, activity, sleep, diet, and total fat gain. Regular exercise and sustainable energy balance provide the strongest foundation for reducing visceral fat.”
“AgeAccelGrim showed strong associations with time-to-death, coronary heart disease, cancer, fatty liver, visceral fat, age at menopause, and comorbidity count. DNAm PAI-1 was especially strongly linked to lifespan, type 2 diabetes, and comorbidity.”
“Menopause, which typically occurs around the age of 52 years, is the cessation of a female's menstrual cycle and signifies the loss of reproductive capacity. Evidence suggests that early menopause increases the risk for age-related disease and premature death.”
“Premature menopause - before the age of 40 - had occurred in one in four (26%) of the women who had had an aneurysm compared with around one in five (19%) of those in the comparison group.”
“Factors that were associated with an earlier age of natural menopause and shorter reproductive lifespan included Black or Hispanic race/ethnicity, poverty, and current and former smoking status. Factors that were associated with a later age of natural menopause and longer reproductive lifespan included greater years of education and oral contraceptive use.”
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