Search results for serotonin

“An evolutionary-biological explanation for why chronic inflammation shunts tryptophan, an important precursor of serotonin, into a neurotoxic pathway that produces a substance called kynurenine, which can become a neurotoxic NMDA agonist known as quinolinic acid that is powerfully associated with depression.”

“###Alcohol, serotonin, and dopamine Many people experience pleasant feelings while drinking, and this occurs through the gamma-aminobutyric acid (GABA, an inhibitory neurotransmitter) system. Some people get more dopamine activation from alcohol.”

“The exercise protocols in the 14 trials ranged from walking to jogging to cycling. The duration range was from 6 weeks to 24 months. Aerobic exercise has been shown to increase brain-derived neurotrophic factor, IGF-1, and serotonin in the brain.”

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“> "We have demonstrated for the first time in an animal model that maternal use of a class of antidepressants called selective serotonin reuptake inhibitors, or SSRIs, resulted in increased fat accumulation and inflammation in the liver of the adult offspring…”

“I'm particularly excited about this research because it confirms my 2014 publication where I proposed that vitamin D regulates serotonin, which is a brain morphogen that shapes the structure and wiring of the brain during early brain development, and that maternal vitamin D deficiency could disrupt fetal brain development and lead to autism.”

“FTA: > We have now discovered that activation of 5-HT(2A) receptors in primary aortic smooth muscle cells provides a previously unknown and extremely potent inhibition of tumor necrosis factor (TNF)-alpha-mediated inflammation. [...] With the exception of a few natural toxins, no current drugs or small molecule therapeutics demonstrate a comparable potency for any physiological effect”