1500mg/day of Vitamin C reduced ultramarathon post-race cortisol and interleukins IL-6, IL-8, and IL-10
“Vitamin C may have a special role in reducing stress-induced cortisol release: > In contrast, others have shown that vitamin C infusion enhances adrenal glucocorticoid production or has no effect on the serum cortisol response to ACTH. Our data suggest that within the context of prolonged and intensive exertion, high vitamin C intake significantly lowers serum cortisol levels.”