Resistance exercise in older adults boosts levels of cardiotrophin-like cytokine factor 1—a myokine released during exercise—by nearly 70%, improving muscle strength, bone density, and metabolic functions.
“Then they restored cardiotrophin-like cytokine factor 1 levels in older mice and found that muscle strength, glucose tolerance, and mitochondrial activity improved. Bone density also increased as the myokine reduced bone-resorbing cells and boosted bone-forming cells.”