Bisphenol A
Episodes
Dr. Rhonda Patrick discusses silicone safety, grounding, pentadecanoic acid, and the potential benefits of olive leaf extract and peptides.
Dr. Rhonda Patrick discusses her supplement stack, avoiding microplastics, creatine for brain health, and mRNA vaccine autoimmunity risks.
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Dr. Rhonda Patrick discusses silicone safety, grounding, pentadecanoic acid, and the potential benefits of olive leaf extract and peptides.
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Dr. Rhonda Patrick discusses her supplement stack, avoiding microplastics, creatine for brain health, and mRNA vaccine autoimmunity risks.
Topic Pages
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Sauna
A sauna exposes the body to ambient temperatures ≈70–100 °C, promoting thermoregulatory vasodilation, perspiration, and transient cardiovascular load.
News & Publications
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Despite the perceived safety of the U.S. food supply, many chemicals used in food packaging and storage may be hazardous. In fact, food scientists have found that more than 1,800 food-contact chemicals migrate into foods—many of which have never undergone toxicity testing. New research demonstrates that more than 3,600 of these toxic compounds have been detected in humans.
Researchers compared a list of more than 14,000 known food-contact chemicals to five major biomonitoring programs and several databases that track chemicals in the human body. They then prioritized chemicals frequently found in food packaging and examined evidence for their presence in humans.
They found that 3,601 of these chemicals have been detected in humans. Of these, 194 were identified in biomonitoring programs, 80 of which carry a high toxicity risk. They also confirmed that 63 of 175 chemicals of concern were present in the human body, and most lacked safety data.
These findings suggest that human exposure to food-contact chemicals is widespread, highlighting the need for stricter safety regulations. Many food-contact chemicals include bisphenol A, phthalates, and other toxic substances that promote cancer, impair fertility, and disrupt hormone signaling. Although many of these compounds accumulate in the body over time, some are preferentially excreted in sweat. Learn how sauna use promotes sweating, helping the body rid itself of some toxic substances.
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Microplastic accumulation in arterial plaques increases the risk for cardiovascular disease-related events nearly fivefold. www.nbcnews.com
Tiny plastic particles, often called microplastics – ranging between 5 millimeters and 100 nanometers – are ubiquitous environmental pollutants. Scientists have identified microplastics in food (especially seafood), soil, drinking water, fresh- and saltwater bodies, and air. A recent study found that microplastics accumulate in human arterial plaques, increasing the risk for cardiovascular disease-related events, such as heart attack or stroke, nearly fivefold.
The study involved 257 patients undergoing carotid endarterectomy, a procedure in which a surgeon removes plaques from the heart’s arteries. Researchers analyzed the plaque for the presence of microplastics, measured the patients' inflammatory biomarkers, and tracked their health for about three years.
They found that more than half of the patients (58.4 percent) had microplastics in their arterial plaques, appearing as jagged-edged foreign particles. Those with microplastics in their plaques were 4.53 times more likely to experience a cardiovascular disease-related event during the three-year follow-up than those without microplastics. They were also more likely to be male, younger, and have diabetes, cardiovascular disease, abnormal blood lipids, and higher inflammatory markers.
These findings suggest that microplastics, a ubiquitous environmental pollutant, accumulate in arterial plaques, markedly increasing the risk of cardiovascular disease-related events. Evidence indicates that microplastic exposure is associated with many other adverse health outcomes. For example, a comprehensive review of the effects of microplastics revealed that microplastics induce oxidative stress and increase the risk for metabolic dysfunction, neurotoxicity, and some cancers. Some of these effects may be due to compounds commonly associated with plastic manufacturing, such as bisphenol A, or BPA, phthalates, and heavy metals that are present in and on microplastics.
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Bisphenol A (BPA) is a chemical used during the production of polycarbonate plastics and epoxy resins. BPA is classified as an endocrine disruptor because it can mimic naturally-occurring hormones in the body such as estrogens, androgens, and thyroid hormones, potentially altering normal hormonal signals. Several chronic diseases are associated with BPA exposure, including hypertension, central obesity, hyperlipidemia, and cancer. Findings from a new study indicate that the FDA’s current methods for gauging BPA exposure levels in humans may be inadequate.
Following oral ingestion of BPA, the body breaks down the chemical into several metabolites, which are then excreted in the urine. Current methods for measuring urinary BPA, which rely on indirect measures, may not accurately estimate human exposure, however. The authors of this study developed a technique that relied on direct measures of BPA and its metabolites in human urine. They found that the indirect assay grossly underestimated actual human levels of BPA exposure. In pregnant women, in particular, urinary BPA levels were 44 times higher than indirect measures reflected.
BPA exposure is widespread due to extensive use of plastics and other BPA-containing products, with an estimated 9 million tons of the chemical produced every year. Food and water, which are commonly packaged in plastic, are common vehicles for BPA exposure. Previous research suggests that the tolerable daily intake of BPA established by the FDA is as much as 20,000 times higher than the levels at which adverse effects have been observed. The findings from this study highlight the need for more accurate measures of human BPA exposure and more research to determine safe levels of exposure.