Related Episodes for A Small Trial Tested Meal Timing and Nighttime Blood Pressure

“Roughly one-quarter of people living in the US carry a genetic variant of the apolipoprotein E gene, called APOE4, the most important genetic risk factor for Alzheimer's disease. Many lifestyle behaviors can mitigate risk, especially sleep hygiene, which provides an opportunity to rid the brain of toxic metabolic byproducts that can contribute to Alzheimer's disease risk.”

“Late-night eating can have negative effects on our health. But time-restricted eating limits the daytime window during which a person eats to take advantage of the time when metabolism is optimized, improving health and even promoting weight loss.”

“Lifestyle factors, such as exercise, nutrition, sleep, and others, can temper some of the risks associated with carrying APOE4. This Aliquot focuses on the ones that can have the greatest benefits – and the ones that do the most harm.”

“Genetic predisposition, altered glucose uptake in the brain, high blood pressure, and other factors can weaken the barrier's integrity, allowing endotoxins and inflammatory immune cells to infiltrate the brain and increasing a person's risk for dementia.”

“According to the latest research on fed vs. fasted exercise: If your workout lasts longer than 60 minutes, especially aerobic (endurance-based) sessions, eating beforehand tends to improve performance Your body has quick access to glucose, which helps you go longer and harder.”

“Some researchers have hypothesized that since antihypertensive drugs like ACE inhibitors and angiotensin II receptor blockers, or ARBs, increase ACE2, they might alter the risk of severe COVID-19 disease.”

“He reserves melatonin and phosphatidylserine for jet lag. He presents these as his personal practices. Dr. Attia also reports drinking anywhere from zero to seven or eight alcoholic drinks per week, no more than two in a day and usually with dinner.”

“In a separate analysis of seven intervention trials involving people with type 2 diabetes, HbA1c fell by about 0.71 percentage points, total cholesterol by 23 mg/dL, and LDL cholesterol by 22 mg/dL.”

“In this clip from Dr. Rhonda Patrick’s appearance on MedCram, she describes sauna as an exercise mimetic because heat raises heart rate, blood flow, plasma volume, and sweating and can lower blood pressure afterward. It does not reproduce every adaptation or replace exercise.”

“In a six-month trial of adults with peripheral artery disease, a flavanol-rich cocoa beverage improved six-minute walking distance measured 2.5 hours after dosing. In older adults with mild cognitive impairment, higher-flavanol cocoa improved selected verbal-fluency and executive-function tests over eight weeks.”